We are very pleased with them and we look forward to doing business with your company in the near future. Estradiol is the most important intracellular human estrogen and is much stronger than its metabolites estrone and estriol at the prescription level. It is recommended to discuss the package leaflet of patients prescribed by Climara. Although you have increased while on estrogen, studies indicate that estrogen does not significantly increase weight gain. Two three thousand and twenty women from the original HERS study agreed to participate in an open extension of Hers, Her II. If you are concerned, contact your doctor or Gift Control Center (Australia: 13 11 26 or New Zealand: 0800 POISON or 0800 764 766) to get advice or go to an emergency and emergency at the nearest hospital if you think you or someone else another might too much climara.